Blog - Reagents

03/12/2025

Escaping Aggregation: Traceless Linkers for Hydrophobic Peptides

Struggling with aggregating peptides or poor solubility? Take the rescue route: introduce solubility tags with our removable linkers. Learn more about your linker choices in our blog.
05/11/2025

T-BEC - An Advanced Carbodiimide for SPPS

Optimize your coupling pathway with T-BEC! Unlike DIC, T-BEC prevents HCN formation when used with OxymaPure. Discover the safe, reliable, and efficient route to amide bonds!
22/10/2025

DMTMMT: High-Performance Triazine Coupling Reagent

Triazine-based coupling reagents, such as DMTMMT, enable a rapid and high-yield synthesis of peptides and esters via a "superactive ester" mechanism. Read our blog!
08/10/2025

PotM: Novel Amino Acid Activators for Molecular Reactors

Carboxylated OxymaPure & HOBt derivatives open the door to ribosome-mimicking molecular reactors to increase coupling efficiency for sterically demanding amino acids. Learn more!
24/09/2025

Products for Green Peptide Chemistry

Recent years have seen major advances in greener peptide synthesis. To highlight such products, we introduced the category "Green Chemistry" on our website. 
27/08/2025

Thioethoxyglycine: A Versatile Reagent for Isopeptide Bond Formation

Amido side-chain modifications via isopeptide bond formation can be achieved by using hydrazides in combination with a thioethoxyglycine linker. Curious how it works? 
16/07/2025

PotM: Novel Bifunctional Linkers for Sequential Click Conjugations

Ynamines are uniquely reactive alkynes with which azides react preferentially, even in the presence of other alkynes. Learn how to take advantage of their selectivity. 
04/06/2025

PotM: AMDBH, a Novel Aldehyde Scavenger for Thz Deprotection in NCL

Take advantage of AMDBH, our novel formaldehyde scavenger in Thz deprotection and simplify the synthesis of long peptides by skipping intermediate purification in Native Chemical Ligation. 
21/05/2025

2DPBM - A Biocompatible Azide Reducing Agent

Reveal what is hidden - even in cells! 2DPBM enables selective and biocompatible azide reduction to amines for orthogonal protection strategies in peptide synthesis.
07/05/2025

PotM: DMSO-EtOAc Mixtures for SPPS as Greener Alternative to DMF

Cut the ecological footprint of your peptide synthesis - and your costs -  by switching from DMF to DMSO-EtOAc mixtures. Increase your sustainability in SPPS!