Blog - Green Chemistry

24/09/2025

Products for Green Peptide Chemistry

Recent years have seen major advances in greener peptide synthesis. To highlight such products, we introduced the category "Green Chemistry" on our website. 
24/09/2025

The Safety-Catch Noki-Linker

The Noki-Linker is designed to make peptide synthesis more sustainable while delivering cleaner products. With a build-in safety-catch, it reduces TFA usage. Curious how? Read on!
30/07/2025

Enzyme-Mediated Ligation

From fragments to full peptides - ligases like e.g., Sortase, Omniligase, enable efficient ligation and cyclization. Read our blog and learn how enzymatic tools can enhance your peptide synthesis.
21/05/2025

2DPBM - A Biocompatible Azide Reducing Agent

Reveal what is hidden - even in cells! 2DPBM enables selective and biocompatible azide reduction to amines for orthogonal protection strategies in peptide synthesis.
07/05/2025

PotM: DMSO-EtOAc Mixtures for SPPS as Greener Alternative to DMF

Cut the ecological footprint of your peptide synthesis - and your costs -  by switching from DMF to DMSO-EtOAc mixtures. Increase your sustainability in SPPS!
26/03/2025

Preloaded Hydrazide Resins for Greener Peptide Synthesis

Improve your synthesis and avoid undesirable solvents! Use our hydrazine resins - preloaded with hydrazine or amino acid hydrazides - to generate peptide fragments for NCL. 
10/03/2025

Solid-Phase Synthesis of Peptide Hydrazides: Moving Toward Green Chemistry

Discover a greener synthetic approach towards peptide hydrazides - valuable precursors, e.g., for the synthesis of peptide thioesters, widely applied building blocks for native chemical ligation. 
12/02/2025

Preloaded MPPA-Li Resin and Rink-Li Resin

Take advantage of our novel pre-loaded Li resins and bring your peptide synthesis to a "greener" level by employing water or other environmentally more friendly solvents! 
15/10/2024

PotM: MYTsA – A Novel Ynamide Coupling Reagent

Discover MYTsA as coupling reagent for peptide synthesis in “traditional” C→N and vice versa in “natural” N→C direction. Avoid racemization and benefit of improved atom economy!
02/10/2024

Hidden Champion – The Tetrahydropyranyl Protective Group

Tetrahydropyranyl (THP) is an excellent protective group for hydroxy and thiol moieties but rarely used in solid-phase peptide synthesis (SPPS). Discover its advantages, e.g., over O/StBu and Trt.