Blog - Building Blocks
22/10/2025
Locked Nucleic Acid (LNA) Phosphoramidites
LNA Building blocks improve duplex stability and binding specificity of oligos by locking the sugar backbone into a rigid 3'-endo envelope conformation. Explore their unique advantages!
24/09/2025
Products for Green Peptide Chemistry
Recent years have seen major advances in greener peptide synthesis. To highlight such products, we introduced the category "Green Chemistry" on our website.
10/09/2025
2'-Modifications of Nucleic Acid Building Blocks
The 2'-position of the ribose sugar wears many hats: enhancing stability, extending half-life, and boosting target binding of DNA/RNA. Discover available modifications & explore their benefits!
13/08/2025
PotM: Phosphoramidites for Oligonucleotide Synthesis
Building on our peptide chemistry expertise, we set sail into new waters, offering nucleic acid building blocks for oligonucleotide synthesis to expand innovation across biomolecular research.
30/07/2025
Extending the Serum Half-life of Therapeutic Peptides
Anchor your peptides: Unlock the secrets of defying protease attacks and extend the serum half-life of your next peptide medication. Our building blocks will help you to reach your goals.
30/07/2025
Enzyme-Mediated Ligation
From fragments to full peptides - ligases like e.g., Sortase, Omniligase, enable efficient ligation and cyclization. Read our blog and learn how enzymatic tools can enhance your peptide synthesis.
23/04/2025
Photosensitive Nitroindoline Amino Acid Analogs
A photolabile anchor for SPPS that facilitates the synthesis of thioesters for native chemical ligation and which can be used to generate peptide chains fragmenting by flash photolysis. To discover NIC, read on!
23/04/2025
4-N3-OBzl-protected Asp and Glu Derivatives
New azidobenzyl side-chain-protected aspartic and glutamic acid building blocks allowing, e.g., for selective reductive deprotection even in physiological systems.
26/03/2025
PotM: Semaglutide and Peptide-Based Weight-Loss Drugs
The example of Semaglutide: Improve the pharmacokinetics of your therapeutic peptides by increasing their resistance against proteases via binding to plasma proteins.
13/03/2025
UAA! Discover Aminocoumarinyl Lysine
We say "UAA"! By genetic code expansion you can incorporate our novel aminocoumarinyl lysine in your favorite protein where it serves you as fluorescent probe or photo-activatable caged lysine.